Cheap flights from Arequipa to Santa Cruz

One-way fares from $223 · AQP → SRZ · prices found by travellers in the last 48 hours

Compare all dates Santa Cruz → Arequipa
Cheapest fare
$223

JetSmart · Thu, Feb 25

Cheapest month
February

from $223

Direct flights
Not recently

Usually 1+ stop

Quickest trip
4h 18m

900 km

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Cheapest month to fly from Arequipa to Santa Cruz

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. February 2027 Cheapest $223

Cheapest dates in February 2027

The lowest fares we've seen for each day, cheapest first.

JetSmart
Depart20:52 Thu, Feb 25AQP → VVI 4h 18m · 1 stop
$223one way, per person
View deal
See every date in February 2027 →

Plan the rest of your trip to Santa Cruz

Where to stay, what to do and getting around, from our travel partners.

Where to stay

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Things to do

Things to do in Santa CruzTours, attractions and day trips on Klook Explore →

Getting around

Airport transfer in Santa CruzPre-book a driver to meet you at arrivals, with Kiwitaxi Book a transfer → Car hire in Santa CruzCompare rental cars from major brands on EconomyBookings Compare cars →

About flights from Arequipa to Santa Cruz

Arequipa (AQP) and Santa Cruz (SRZ) are about 900 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 4h 18m. Over the next few months, one-way fares start from $223, and February 2027 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Arequipa to Santa Cruz?

The cheapest one-way fare we've seen recently is $223 with JetSmart, departing Thursday, February 25, 2027.

What is the cheapest month to fly from Arequipa to Santa Cruz?

February 2027 currently has the lowest fares, from $223 one way.

Are there direct flights from Arequipa to Santa Cruz?

We haven't seen direct fares recently, so most journeys include at least one stop.

How long is the flight from Arequipa to Santa Cruz?

The quickest journey we've seen takes about 4h 18m. Arequipa and Santa Cruz are around 900 km apart.

Which airlines fly from Arequipa to Santa Cruz?

Recent fares on this route were with JetSmart.

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