Cheap flights from Cayenne to Santiago

One-way fares from $1,979 · CAY → SCL · prices found by travellers in the last 48 hours

Cheapest fare
$1,979

Air France · Tue, Nov 10

Cheapest month
November

from $1,979

Direct flights
Not recently

Usually 1+ stop

Quickest trip
27h 25m

4,680 km

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Cheapest month to fly from Cayenne to Santiago

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 Cheapest $1,979

Cheapest dates in November 2026

The lowest fares we've seen for each day, cheapest first.

Air France
Depart17:15 Tue, Nov 10CAY → SCL 27h 25m · 3 stops
$1,979one way, per person
View deal
See every date in November 2026 →

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Where to stay, what to do and getting around, from our travel partners.

About flights from Cayenne to Santiago

Cayenne (CAY) and Santiago (SCL) are about 4,680 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 27h 25m. Over the next few months, one-way fares start from $1,979, and November 2026 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Cayenne to Santiago?

The cheapest one-way fare we've seen recently is $1,979 with Air France, departing Tuesday, November 10, 2026.

What is the cheapest month to fly from Cayenne to Santiago?

November 2026 currently has the lowest fares, from $1,979 one way.

Are there direct flights from Cayenne to Santiago?

We haven't seen direct fares recently, so most journeys include at least one stop.

How long is the flight from Cayenne to Santiago?

The quickest journey we've seen takes about 27h 25m. Cayenne and Santiago are around 4,680 km apart.

Which airlines fly from Cayenne to Santiago?

Recent fares on this route were with Air France.

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