American AirlinesDepart20:00
Fri, Nov 13CRW → TYS
3h 24m · 1 stop
$394one way, per person
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- Cheapest fare
- $394
- Cheapest month
- November
- Direct flights
- Not recently
- Quickest trip
- 3h 24m
American Airlines · Fri, Nov 13
from $394
Usually 1+ stop
340 km
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Cheapest month to fly from Charleston to Knoxville
Lowest one-way fare per person in each month. Choose a month to see every date.
Cheapest dates in November 2026
The lowest fares we've seen for each day, cheapest first.
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About flights from Charleston to Knoxville
Charleston (CRW) and Knoxville (TYS) are about 340 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 3h 24m. Over the next few months, one-way fares start from $394, and November 2026 is currently the cheapest month to fly.
These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.
Frequently asked questions
How much is a flight from Charleston to Knoxville?
The cheapest one-way fare we've seen recently is $394 with American Airlines, departing Friday, November 13, 2026.
What is the cheapest month to fly from Charleston to Knoxville?
November 2026 currently has the lowest fares, from $394 one way.
Are there direct flights from Charleston to Knoxville?
We haven't seen direct fares recently, so most journeys include at least one stop.
How long is the flight from Charleston to Knoxville?
The quickest journey we've seen takes about 3h 24m. Charleston and Knoxville are around 340 km apart.
Which airlines fly from Charleston to Knoxville?
Recent fares on this route were with American Airlines.
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