Cheap flights from Charleston to Santo Domingo

One-way fares from $159 · CHS → SDQ · prices found by travellers in the last 48 hours

Cheapest fare
$159

American Airlines · Sat, Dec 12

Cheapest month
December

from $159

Direct flights
Not recently

Usually 1+ stop

Quickest trip
4h 07m

1,880 km

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Cheapest month to fly from Charleston to Santo Domingo

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. December 2026 Cheapest $159

Cheapest dates in December 2026

The lowest fares we've seen for each day, cheapest first.

American Airlines
Depart20:12 Sat, Dec 12CHS → SDQ 4h 07m · 1 stop
$159one way, per person
View deal
See every date in December 2026 →

Plan the rest of your trip to Santo Domingo

Where to stay, what to do and getting around, from our travel partners.

About flights from Charleston to Santo Domingo

Charleston (CHS) and Santo Domingo (SDQ) are about 1,880 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 4h 07m. Over the next few months, one-way fares start from $159, and December 2026 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Charleston to Santo Domingo?

The cheapest one-way fare we've seen recently is $159 with American Airlines, departing Saturday, December 12, 2026.

What is the cheapest month to fly from Charleston to Santo Domingo?

December 2026 currently has the lowest fares, from $159 one way.

Are there direct flights from Charleston to Santo Domingo?

We haven't seen direct fares recently, so most journeys include at least one stop.

How long is the flight from Charleston to Santo Domingo?

The quickest journey we've seen takes about 4h 07m. Charleston and Santo Domingo are around 1,880 km apart.

Which airlines fly from Charleston to Santo Domingo?

Recent fares on this route were with American Airlines.

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