Cheap flights from Chicago to Guayaquil

One-way fares from $294 · CHI → GYE · prices found by travellers in the last 48 hours

Compare all dates Guayaquil → Chicago
Cheapest fare
$294

Copa Airlines · Tue, Dec 29

Cheapest month
December

from $294

Direct flights
Not recently

Usually 1+ stop

Quickest trip
7h 41m

4,960 km

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Cheapest month to fly from Chicago to Guayaquil

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. December 2026 Cheapest $294

Cheapest dates in December 2026

The lowest fares we've seen for each day, cheapest first.

Copa Airlines
Depart14:13 Tue, Dec 29ORD → GYE 7h 41m · 1 stop
$294one way, per person
View deal
See every date in December 2026 →

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Where to stay, what to do and getting around, from our travel partners.

Where to stay

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Things to do

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Getting around

Airport transfer in GuayaquilPre-book a driver to meet you at arrivals, with Kiwitaxi Book a transfer → Car hire in GuayaquilCompare rental cars from major brands on EconomyBookings Compare cars →

About flights from Chicago to Guayaquil

Chicago (CHI) and Guayaquil (GYE) are about 4,960 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 7h 41m. Over the next few months, one-way fares start from $294, and December 2026 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Chicago to Guayaquil?

The cheapest one-way fare we've seen recently is $294 with Copa Airlines, departing Tuesday, December 29, 2026.

What is the cheapest month to fly from Chicago to Guayaquil?

December 2026 currently has the lowest fares, from $294 one way.

Are there direct flights from Chicago to Guayaquil?

We haven't seen direct fares recently, so most journeys include at least one stop.

How long is the flight from Chicago to Guayaquil?

The quickest journey we've seen takes about 7h 41m. Chicago and Guayaquil are around 4,960 km apart.

Which airlines fly from Chicago to Guayaquil?

Recent fares on this route were with Copa Airlines.

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