Cheap flights from Chicago to Knoxville

One-way fares from $81 · CHI → TYS · prices found by travellers in the last 48 hours

Compare all dates Knoxville → Chicago
Cheapest fare
$81

Allegiant Air · Fri, Nov 13

Cheapest month
November

from $81

Direct flights
Yes

Allegiant Air and American Airlines

Flight time
1h 30m

730 km

Get a price alert

We'll email you when Chicago → Knoxville drops to your price. It's free, and you can stop any time.

Today's cheapest fare is $81. We'll send one email to confirm. See our privacy policy.

Cheapest month to fly from Chicago to Knoxville

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 Cheapest $81

Cheapest dates in November 2026

The lowest fares we've seen for each day, cheapest first.

Allegiant Air
Depart15:16 Fri, Nov 13MDW → TYS 1h 30m · Direct
$81one way, per person
View deal
American Airlines
Depart08:09 Tue, Nov 24ORD → TYS 1h 49m · Direct
$125one way, per person
View deal
American Airlines
Depart16:00 Tue, Nov 10ORD → TYS 1h 46m · Direct
$139one way, per person
View deal
Allegiant Air
Depart09:30 Thu, Nov 12RFD → TYS 5h 15m · 1 stop
$173one way, per person
View deal
Frontier Airlines
Depart07:05 Sat, Nov 7ORD → TYS 5h 52m · 2 stops
$238one way, per person
View deal
See every date in November 2026 →

Plan the rest of your trip to Knoxville

Where to stay, what to do and getting around, from our travel partners.

Where to stay

Hotels in KnoxvilleCompare places to stay on Booking.com Find hotels →

Things to do

Things to do in KnoxvilleTours, attractions and day trips on Klook Explore →

Getting around

Airport transfer in KnoxvillePre-book a driver to meet you at arrivals, with Kiwitaxi Book a transfer → Car hire in KnoxvilleCompare rental cars from major brands on EconomyBookings Compare cars →

About flights from Chicago to Knoxville

Chicago (CHI) and Knoxville (TYS) are about 730 km apart. Direct flights take around 1h 30m, and recent direct fares were with Allegiant Air and American Airlines. Over the next few months, one-way fares start from $81, and November 2026 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Chicago to Knoxville?

The cheapest one-way fare we've seen recently is $81 with Allegiant Air, departing Friday, November 13, 2026.

What is the cheapest month to fly from Chicago to Knoxville?

November 2026 currently has the lowest fares, from $81 one way.

Are there direct flights from Chicago to Knoxville?

Yes. Recent direct fares were with Allegiant Air and American Airlines.

How long is the flight from Chicago to Knoxville?

A direct flight takes about 1h 30m. Chicago and Knoxville are around 730 km apart.

Which airlines fly from Chicago to Knoxville?

Recent fares on this route were with Allegiant Air, American Airlines and Frontier Airlines.

More cheap flights from Chicago

Compare flights to Knoxville from other cities →