Cheap flights from Erie to Knoxville

One-way fares from $490 · ERI → TYS · prices found by travellers in the last 48 hours

Compare all dates Knoxville → Erie
Cheapest fare
$490

American Airlines · Thu, Nov 12

Cheapest month
November

from $490

Direct flights
Not recently

Usually 1+ stop

Quickest trip
3h 19m

760 km

Get a price alert

We'll email you when Erie → Knoxville drops to your price. It's free, and you can stop any time.

Today's cheapest fare is $490. We'll send one email to confirm. See our privacy policy.

Cheapest month to fly from Erie to Knoxville

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 Cheapest $490

Cheapest dates in November 2026

The lowest fares we've seen for each day, cheapest first.

American Airlines
Depart06:00 Thu, Nov 12ERI → TYS 3h 35m · 1 stop
$490one way, per person
View deal
American Airlines
Depart06:00 Fri, Nov 13ERI → TYS 3h 35m · 1 stop
$496one way, per person
View deal
See every date in November 2026 →

Plan the rest of your trip to Knoxville

Where to stay, what to do and getting around, from our travel partners.

Where to stay

Hotels in KnoxvilleCompare places to stay on Booking.com Find hotels →

Things to do

Things to do in KnoxvilleTours, attractions and day trips on Klook Explore →

Getting around

Airport transfer in KnoxvillePre-book a driver to meet you at arrivals, with Kiwitaxi Book a transfer → Car hire in KnoxvilleCompare rental cars from major brands on EconomyBookings Compare cars →

About flights from Erie to Knoxville

Erie (ERI) and Knoxville (TYS) are about 760 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 3h 19m. Over the next few months, one-way fares start from $490, and November 2026 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Erie to Knoxville?

The cheapest one-way fare we've seen recently is $490 with American Airlines, departing Thursday, November 12, 2026.

What is the cheapest month to fly from Erie to Knoxville?

November 2026 currently has the lowest fares, from $490 one way.

Are there direct flights from Erie to Knoxville?

We haven't seen direct fares recently, so most journeys include at least one stop.

How long is the flight from Erie to Knoxville?

The quickest journey we've seen takes about 3h 19m. Erie and Knoxville are around 760 km apart.

Which airlines fly from Erie to Knoxville?

Recent fares on this route were with American Airlines.

More cheap flights from Erie

Compare flights to Knoxville from other cities →