Cheap flights from Iquique to Santa Cruz

One-way fares from $228 · IQQ → SRZ · prices found by travellers in the last 48 hours

Cheapest fare
$228

Boliviana de Aviación · Sat, Dec 26

Cheapest month
December

from $228

Direct flights
Yes

Boliviana de Aviación

Flight time
1h 50m

780 km

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Cheapest month to fly from Iquique to Santa Cruz

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. December 2026 Cheapest $228

Cheapest dates in December 2026

The lowest fares we've seen for each day, cheapest first.

Boliviana de Aviación
Depart17:40 Sat, Dec 26IQQ → VVI 1h 50m · Direct
$228one way, per person
View deal
See every date in December 2026 →

Plan the rest of your trip to Santa Cruz

Where to stay, what to do and getting around, from our travel partners.

About flights from Iquique to Santa Cruz

Iquique (IQQ) and Santa Cruz (SRZ) are about 780 km apart. Direct flights take around 1h 50m, and recent direct fares were with Boliviana de Aviación. Over the next few months, one-way fares start from $228, and December 2026 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Iquique to Santa Cruz?

The cheapest one-way fare we've seen recently is $228 with Boliviana de Aviación, departing Saturday, December 26, 2026.

What is the cheapest month to fly from Iquique to Santa Cruz?

December 2026 currently has the lowest fares, from $228 one way.

Are there direct flights from Iquique to Santa Cruz?

Yes. Recent direct fares were with Boliviana de Aviación.

How long is the flight from Iquique to Santa Cruz?

A direct flight takes about 1h 50m. Iquique and Santa Cruz are around 780 km apart.

Which airlines fly from Iquique to Santa Cruz?

Recent fares on this route were with Boliviana de Aviación.

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