Cheap flights from Jacksonville to St Louis

One-way fares from $264 · JAX → STL · prices found by travellers in the last 48 hours

Compare all dates St Louis → Jacksonville
Cheapest fare
$264

Breeze Airways · Mon, Nov 9

Cheapest month
November

from $264

Direct flights
Not recently

Usually 1+ stop

Quickest trip
7h 08m

1,210 km

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Cheapest month to fly from Jacksonville to St Louis

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 Cheapest $264

Cheapest dates in November 2026

The lowest fares we've seen for each day, cheapest first.

Breeze Airways
Depart15:56 Mon, Nov 9JAX → STL 7h 08m · 3 stops
$264one way, per person
View deal
See every date in November 2026 →

Plan the rest of your trip to St Louis

Where to stay, what to do and getting around, from our travel partners.

Where to stay

Hotels in St LouisCompare places to stay on Booking.com Find hotels →

Things to do

Things to do in St LouisTours, attractions and day trips on Klook Explore →

Getting around

Airport transfer in St LouisPre-book a driver to meet you at arrivals, with Kiwitaxi Book a transfer → Car hire in St LouisCompare rental cars from major brands on EconomyBookings Compare cars →

About flights from Jacksonville to St Louis

Jacksonville (JAX) and St Louis (STL) are about 1,210 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 7h 08m. Over the next few months, one-way fares start from $264, and November 2026 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Jacksonville to St Louis?

The cheapest one-way fare we've seen recently is $264 with Breeze Airways, departing Monday, November 9, 2026.

What is the cheapest month to fly from Jacksonville to St Louis?

November 2026 currently has the lowest fares, from $264 one way.

Are there direct flights from Jacksonville to St Louis?

We haven't seen direct fares recently, so most journeys include at least one stop.

How long is the flight from Jacksonville to St Louis?

The quickest journey we've seen takes about 7h 08m. Jacksonville and St Louis are around 1,210 km apart.

Which airlines fly from Jacksonville to St Louis?

Recent fares on this route were with Breeze Airways.

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