American AirlinesDepart19:35
Sun, Dec 13TYS → GUA
5h 06m · 1 stop
$282one way, per person
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- Cheapest fare
- $282
- Cheapest month
- December
- Direct flights
- Not recently
- Quickest trip
- 5h 06m
American Airlines · Sun, Dec 13
from $282
Usually 1+ stop
2,460 km
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Cheapest month to fly from Knoxville to Guatemala City
Lowest one-way fare per person in each month. Choose a month to see every date.
Cheapest dates in December 2026
The lowest fares we've seen for each day, cheapest first.
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Where to stay, what to do and getting around, from our travel partners.
About flights from Knoxville to Guatemala City
Knoxville (TYS) and Guatemala City (GUA) are about 2,460 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 5h 06m. Over the next few months, one-way fares start from $282, and December 2026 is currently the cheapest month to fly.
These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.
Frequently asked questions
How much is a flight from Knoxville to Guatemala City?
The cheapest one-way fare we've seen recently is $282 with American Airlines, departing Sunday, December 13, 2026.
What is the cheapest month to fly from Knoxville to Guatemala City?
December 2026 currently has the lowest fares, from $282 one way.
Are there direct flights from Knoxville to Guatemala City?
We haven't seen direct fares recently, so most journeys include at least one stop.
How long is the flight from Knoxville to Guatemala City?
The quickest journey we've seen takes about 5h 06m. Knoxville and Guatemala City are around 2,460 km apart.
Which airlines fly from Knoxville to Guatemala City?
Recent fares on this route were with American Airlines.
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