Cheap flights from La Crosse to San Francisco

One-way fares from $523 · LSE → SFO · prices found by travellers in the last 48 hours

Compare all dates San Francisco → La Crosse
Cheapest fare
$523

American Airlines · Fri, Nov 13

Cheapest month
November

from $523

Direct flights
Not recently

Usually 1+ stop

Quickest trip
6h 39m

2,690 km

Get a price alert

We'll email you when La Crosse → San Francisco drops to your price. It's free, and you can stop any time.

Today's cheapest fare is $523. We'll send one email to confirm. See our privacy policy.

Cheapest month to fly from La Crosse to San Francisco

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 Cheapest $523

Plan the rest of your trip to San Francisco

Where to stay, what to do and getting around, from our travel partners.

Where to stay

Hotels in San FranciscoCompare places to stay on Booking.com Find hotels →

Things to do

Things to do in San FranciscoTours, attractions and day trips on Klook Explore →

Getting around

Airport transfer in San FranciscoPre-book a driver to meet you at arrivals, with Kiwitaxi Book a transfer → Car hire in San FranciscoCompare rental cars from major brands on EconomyBookings Compare cars →

About flights from La Crosse to San Francisco

La Crosse (LSE) and San Francisco (SFO) are about 2,690 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 6h 39m. Over the next few months, one-way fares start from $523, and November 2026 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from La Crosse to San Francisco?

The cheapest one-way fare we've seen recently is $523 with American Airlines, departing Friday, November 13, 2026.

What is the cheapest month to fly from La Crosse to San Francisco?

November 2026 currently has the lowest fares, from $523 one way.

Are there direct flights from La Crosse to San Francisco?

We haven't seen direct fares recently, so most journeys include at least one stop.

How long is the flight from La Crosse to San Francisco?

The quickest journey we've seen takes about 6h 39m. La Crosse and San Francisco are around 2,690 km apart.

Which airlines fly from La Crosse to San Francisco?

Recent fares on this route were with American Airlines.

More cheap flights from La Crosse

Compare flights to San Francisco from other cities →