Cheap flights from Madrid to Santiago

One-way fares from €387 · MAD → SCL · prices found by travellers in the last 48 hours

Cheapest fare
€387

Iberia · Sun, 7 Mar

Cheapest month
March

from €387

Direct flights
Yes

Iberia and LATAM Airlines Group

Flight time
13h 20m

10,700 km

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Cheapest month to fly from Madrid to Santiago

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 €547
  2. December 2026 €472
  3. January 2027 €478
  4. February 2027 €412
  5. March 2027 Cheapest €387
  6. May 2027 €430

Cheapest dates in March 2027

The lowest fares we've seen for each day, cheapest first.

Iberia
Depart13:00 Sun, 7 MarMAD → SCL 13h 20m · Direct
€387one way, per person
View deal
Iberia
Depart23:59 Mon, 8 MarMAD → SCL 13h 21m · Direct
€387one way, per person
View deal
Iberia
Depart13:00 Tue, 2 MarMAD → SCL 13h 20m · Direct
€417one way, per person
View deal
Iberia
Depart13:00 Thu, 4 MarMAD → SCL 13h 20m · Direct
€417one way, per person
View deal
avianca airlines
Depart08:10 Sat, 6 MarMAD → SCL 16h 20m · 1 stop
€442one way, per person
View deal
avianca airlines
Depart08:10 Sat, 13 MarMAD → SCL 16h 20m · 1 stop
€492one way, per person
View deal
See every date in March 2027 →

Plan the rest of your trip to Santiago

Where to stay, what to do and getting around, from our travel partners.

About flights from Madrid to Santiago

Madrid (MAD) and Santiago (SCL) are about 10,700 km apart. Direct flights take around 13h 20m, and recent direct fares were with Iberia and LATAM Airlines Group. Over the next few months, one-way fares start from €387, and March 2027 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Madrid to Santiago?

The cheapest one-way fare we've seen recently is €387 with Iberia, departing Sunday, 7 March 2027. Over the coming months, the lowest fare in each month ranges from €387 to €547.

What is the cheapest month to fly from Madrid to Santiago?

March 2027 currently has the lowest fares, from €387 one way.

Are there direct flights from Madrid to Santiago?

Yes. Recent direct fares were with Iberia and LATAM Airlines Group.

How long is the flight from Madrid to Santiago?

A direct flight takes about 13h 20m. Madrid and Santiago are around 10,700 km apart.

Which airlines fly from Madrid to Santiago?

Recent fares on this route were with Iberia Express, United Airlines, avianca airlines, Iberia and LATAM Airlines Group.

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