Cheap flights from Madrid to Santiago

One-way fares from €476 · MAD → STI · prices found by travellers in the last 48 hours

Compare all dates Santiago → Madrid
Cheapest fare
€476

Air Europa · Sat, 7 Nov

Cheapest month
November

from €476

Direct flights
Yes

Air Europa

Flight time
8h 50m

6,690 km

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Cheapest month to fly from Madrid to Santiago

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 Cheapest €476

Cheapest dates in November 2026

The lowest fares we've seen for each day, cheapest first.

Air Europa
Depart17:10 Sat, 7 NovMAD → STI 8h 50m · Direct
€476one way, per person
View deal
TAP Air Portugal
Depart12:10 Wed, 4 NovMAD → STI 13h 34m · 2 stops
€680one way, per person
View deal
See every date in November 2026 →

Plan the rest of your trip to Santiago

Where to stay, what to do and getting around, from our travel partners.

Where to stay

Hotels in SantiagoCompare places to stay on Booking.com Find hotels →

Things to do

Things to do in SantiagoTours, attractions and day trips on Klook Explore →

Getting around

Airport transfer in SantiagoPre-book a driver to meet you at arrivals, with Kiwitaxi Book a transfer → Car hire in SantiagoCompare rental cars from major brands on EconomyBookings Compare cars →

About flights from Madrid to Santiago

Madrid (MAD) and Santiago (STI) are about 6,690 km apart. Direct flights take around 8h 50m, and recent direct fares were with Air Europa. Over the next few months, one-way fares start from €476, and November 2026 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Madrid to Santiago?

The cheapest one-way fare we've seen recently is €476 with Air Europa, departing Saturday, 7 November 2026.

What is the cheapest month to fly from Madrid to Santiago?

November 2026 currently has the lowest fares, from €476 one way.

Are there direct flights from Madrid to Santiago?

Yes. Recent direct fares were with Air Europa.

How long is the flight from Madrid to Santiago?

A direct flight takes about 8h 50m. Madrid and Santiago are around 6,690 km apart.

Which airlines fly from Madrid to Santiago?

Recent fares on this route were with Air Europa and TAP Air Portugal.

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