Cheap flights from Manaus to Panama City

One-way fares from $223 · MAO → PTY · prices found by travellers in the last 48 hours

Cheapest fare
$223

avianca airlines · Mon, Nov 16

Cheapest month
November

from $223

Direct flights
Not recently

Usually 1+ stop

Quickest trip
4h 45m

2,550 km

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Cheapest month to fly from Manaus to Panama City

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 Cheapest $223
  2. December 2026 $261
  3. January 2027 $253
  4. February 2027 $228

Cheapest dates in November 2026

The lowest fares we've seen for each day, cheapest first.

avianca airlines
Depart04:05 Mon, Nov 16MAO → PTY 4h 45m · 1 stop
$223one way, per person
View deal
See every date in November 2026 →

Plan the rest of your trip to Panama City

Where to stay, what to do and getting around, from our travel partners.

About flights from Manaus to Panama City

Manaus (MAO) and Panama City (PTY) are about 2,550 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 4h 45m. Over the next few months, one-way fares start from $223, and November 2026 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Manaus to Panama City?

The cheapest one-way fare we've seen recently is $223 with avianca airlines, departing Monday, November 16, 2026. Over the coming months, the lowest fare in each month ranges from $223 to $261.

What is the cheapest month to fly from Manaus to Panama City?

November 2026 currently has the lowest fares, from $223 one way.

Are there direct flights from Manaus to Panama City?

We haven't seen direct fares recently, so most journeys include at least one stop.

How long is the flight from Manaus to Panama City?

The quickest journey we've seen takes about 4h 45m. Manaus and Panama City are around 2,550 km apart.

Which airlines fly from Manaus to Panama City?

Recent fares on this route were with avianca airlines.

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