Cheap flights from Manhattan to Greenville

One-way fares from $541 · MHK → GSP · prices found by travellers in the last 48 hours

Compare all dates Greenville → Manhattan
Cheapest fare
$541

American Airlines · Fri, Nov 13

Cheapest month
November

from $541

Direct flights
Not recently

Usually 1+ stop

Quickest trip
4h 01m

1,350 km

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Cheapest month to fly from Manhattan to Greenville

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 Cheapest $541

Cheapest dates in November 2026

The lowest fares we've seen for each day, cheapest first.

American Airlines
Depart07:06 Fri, Nov 13MHK → GSP 4h 01m · 1 stop
$541one way, per person
View deal
See every date in November 2026 →

Plan the rest of your trip to Greenville

Where to stay, what to do and getting around, from our travel partners.

Where to stay

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Things to do

Things to do in GreenvilleTours, attractions and day trips on Klook Explore →

Getting around

Airport transfer in GreenvillePre-book a driver to meet you at arrivals, with Kiwitaxi Book a transfer → Car hire in GreenvilleCompare rental cars from major brands on EconomyBookings Compare cars →

About flights from Manhattan to Greenville

Manhattan (MHK) and Greenville (GSP) are about 1,350 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 4h 01m. Over the next few months, one-way fares start from $541, and November 2026 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Manhattan to Greenville?

The cheapest one-way fare we've seen recently is $541 with American Airlines, departing Friday, November 13, 2026.

What is the cheapest month to fly from Manhattan to Greenville?

November 2026 currently has the lowest fares, from $541 one way.

Are there direct flights from Manhattan to Greenville?

We haven't seen direct fares recently, so most journeys include at least one stop.

How long is the flight from Manhattan to Greenville?

The quickest journey we've seen takes about 4h 01m. Manhattan and Greenville are around 1,350 km apart.

Which airlines fly from Manhattan to Greenville?

Recent fares on this route were with American Airlines.

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