avianca airlinesDepart14:15
Thu, Dec 24MZL → PTY
3h 27m · 2 stops
$496one way, per person
View deal
- Cheapest fare
- $496
- Cheapest month
- December
- Direct flights
- Not recently
- Quickest trip
- 2h 45m
avianca airlines · Thu, Dec 24
from $496
Usually 1+ stop
620 km
Get a price alert
We'll email you when Manizales → Panama City drops to your price. It's free, and you can stop any time.
Today's cheapest fare is $496. We'll send one email to confirm. See our privacy policy.
Cheapest month to fly from Manizales to Panama City
Lowest one-way fare per person in each month. Choose a month to see every date.
Cheapest dates in December 2026
The lowest fares we've seen for each day, cheapest first.
avianca airlinesPlan the rest of your trip to Panama City
Where to stay, what to do and getting around, from our travel partners.
About flights from Manizales to Panama City
Manizales (MZL) and Panama City (PTY) are about 620 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 2h 45m. Over the next few months, one-way fares start from $496, and December 2026 is currently the cheapest month to fly.
These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.
Frequently asked questions
How much is a flight from Manizales to Panama City?
The cheapest one-way fare we've seen recently is $496 with avianca airlines, departing Thursday, December 24, 2026. Over the coming months, the lowest fare in each month ranges from $496 to $524.
What is the cheapest month to fly from Manizales to Panama City?
December 2026 currently has the lowest fares, from $496 one way.
Are there direct flights from Manizales to Panama City?
We haven't seen direct fares recently, so most journeys include at least one stop.
How long is the flight from Manizales to Panama City?
The quickest journey we've seen takes about 2h 45m. Manizales and Panama City are around 620 km apart.
Which airlines fly from Manizales to Panama City?
Recent fares on this route were with Clic and avianca airlines.