United AirlinesDepart05:00
Sat, Dec 12MFE → PTY
5h 38m · 1 stop
$422one way, per person
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- Cheapest fare
- $422
- Cheapest month
- December
- Direct flights
- Not recently
- Quickest trip
- 5h 37m
United Airlines · Sat, Dec 12
from $422
Usually 1+ stop
2,750 km
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Cheapest month to fly from McAllen to Panama City
Lowest one-way fare per person in each month. Choose a month to see every date.
Cheapest dates in December 2026
The lowest fares we've seen for each day, cheapest first.
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About flights from McAllen to Panama City
McAllen (MFE) and Panama City (PTY) are about 2,750 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 5h 37m. Over the next few months, one-way fares start from $422, and December 2026 is currently the cheapest month to fly.
These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.
Frequently asked questions
How much is a flight from McAllen to Panama City?
The cheapest one-way fare we've seen recently is $422 with United Airlines, departing Saturday, December 12, 2026.
What is the cheapest month to fly from McAllen to Panama City?
December 2026 currently has the lowest fares, from $422 one way.
Are there direct flights from McAllen to Panama City?
We haven't seen direct fares recently, so most journeys include at least one stop.
How long is the flight from McAllen to Panama City?
The quickest journey we've seen takes about 5h 37m. McAllen and Panama City are around 2,750 km apart.
Which airlines fly from McAllen to Panama City?
Recent fares on this route were with United Airlines.