Cheap flights from Mendoza to Santiago

One-way fares from $55 · MDZ → SCL · prices found by travellers in the last 48 hours

Compare all dates Santiago → Mendoza
Cheapest fare
$55

Sky Airline · Thu, Nov 12

Cheapest month
November

from $55

Direct flights
Yes

Sky Airline, JetSmart and LATAM Airlines Group

Flight time
0h 57m

180 km

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Cheapest month to fly from Mendoza to Santiago

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 Cheapest $55
  2. December 2026 $55
  3. February 2027 $58
  4. March 2027 $65

Cheapest dates in November 2026

The lowest fares we've seen for each day, cheapest first.

Sky Airline
Depart16:00 Thu, Nov 12MDZ → SCL 1h 01m · Direct
$55one way, per person
View deal
LATAM Airlines Group
Depart19:50 Tue, Nov 24MDZ → SCL 0h 57m · Direct
$68one way, per person
View deal
Sky Airline
Depart16:00 Wed, Nov 18MDZ → SCL 1h 02m · Direct
$99one way, per person
View deal
Sky Airline
Depart16:00 Sat, Nov 28MDZ → SCL 1h 02m · Direct
$100one way, per person
View deal
Sky Airline
Depart16:00 Fri, Nov 20MDZ → SCL 1h 02m · Direct
$101one way, per person
View deal
Sky Airline
Depart16:00 Mon, Nov 9MDZ → SCL 1h 02m · Direct
$103one way, per person
View deal
Sky Airline
Depart16:00 Mon, Nov 16MDZ → SCL 1h 02m · Direct
$116one way, per person
View deal
LATAM Airlines Group
Depart12:15 Sun, Nov 15MDZ → SCL 0h 57m · Direct
$182one way, per person
View deal
See every date in November 2026 →

Plan the rest of your trip to Santiago

Where to stay, what to do and getting around, from our travel partners.

Where to stay

Hotels in SantiagoCompare places to stay on Booking.com Find hotels →

Things to do

Things to do in SantiagoTours, attractions and day trips on Klook Explore →

Getting around

Airport transfer in SantiagoPre-book a driver to meet you at arrivals, with Kiwitaxi Book a transfer → Car hire in SantiagoCompare rental cars from major brands on EconomyBookings Compare cars →

Stay connected

eSIM for ChileMobile data from the moment you land, by Airalo Get eSIM →

About flights from Mendoza to Santiago

Mendoza (MDZ) and Santiago (SCL) are about 180 km apart. Direct flights take around 0h 57m, and recent direct fares were with Sky Airline, JetSmart and LATAM Airlines Group. Over the next few months, one-way fares start from $55, and November 2026 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Mendoza to Santiago?

The cheapest one-way fare we've seen recently is $55 with Sky Airline, departing Thursday, November 12, 2026. Over the coming months, the lowest fare in each month ranges from $55 to $65.

What is the cheapest month to fly from Mendoza to Santiago?

November 2026 currently has the lowest fares, from $55 one way.

Are there direct flights from Mendoza to Santiago?

Yes. Recent direct fares were with Sky Airline, JetSmart and LATAM Airlines Group.

How long is the flight from Mendoza to Santiago?

A direct flight takes about 0h 57m. Mendoza and Santiago are around 180 km apart.

Which airlines fly from Mendoza to Santiago?

Recent fares on this route were with Sky Airline, JetSmart and LATAM Airlines Group.

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