Cheap flights from Mexico City to Santo Domingo

One-way fares from $163 · MEX → SDQ · prices found by travellers in the last 48 hours

Cheapest fare
$163

Arajet · Thu, Jan 21

Cheapest month
January

from $163

Direct flights
Yes

Arajet and Aeromexico

Flight time
4h 15m

3,070 km

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Cheapest month to fly from Mexico City to Santo Domingo

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 $276
  2. December 2026 $275
  3. January 2027 Cheapest $163
  4. February 2027 $174
  5. May 2027 $329

Cheapest dates in January 2027

The lowest fares we've seen for each day, cheapest first.

Arajet
Depart23:34 Thu, Jan 21NLU → SDQ 4h 15m · Direct
$163one way, per person
View deal
Arajet
Depart23:34 Thu, Jan 28NLU → SDQ 4h 15m · Direct
$163one way, per person
View deal
Copa Airlines
Depart09:10 Sun, Jan 3MEX → SDQ 6h 12m · 1 stop
$387one way, per person
View deal
See every date in January 2027 →

Plan the rest of your trip to Santo Domingo

Where to stay, what to do and getting around, from our travel partners.

About flights from Mexico City to Santo Domingo

Mexico City (MEX) and Santo Domingo (SDQ) are about 3,070 km apart. Direct flights take around 4h 15m, and recent direct fares were with Arajet and Aeromexico. Over the next few months, one-way fares start from $163, and January 2027 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Mexico City to Santo Domingo?

The cheapest one-way fare we've seen recently is $163 with Arajet, departing Thursday, January 21, 2027. Over the coming months, the lowest fare in each month ranges from $163 to $329.

What is the cheapest month to fly from Mexico City to Santo Domingo?

January 2027 currently has the lowest fares, from $163 one way.

Are there direct flights from Mexico City to Santo Domingo?

Yes. Recent direct fares were with Arajet and Aeromexico.

How long is the flight from Mexico City to Santo Domingo?

A direct flight takes about 4h 15m. Mexico City and Santo Domingo are around 3,070 km apart.

Which airlines fly from Mexico City to Santo Domingo?

Recent fares on this route were with Arajet, Aeromexico and Copa Airlines.

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