Cheap flights from Myrtle Beach to Louisville

One-way fares from $262 · MYR → SDF · prices found by travellers in the last 48 hours

Cheapest fare
$262

American Airlines · Mon, Nov 16

Cheapest month
November

from $262

Direct flights
Not recently

Usually 1+ stop

Quickest trip
2h 33m

800 km

Get a price alert

We'll email you when Myrtle Beach → Louisville drops to your price. It's free, and you can stop any time.

Today's cheapest fare is $262. We'll send one email to confirm. See our privacy policy.

Cheapest month to fly from Myrtle Beach to Louisville

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 Cheapest $262

Cheapest dates in November 2026

The lowest fares we've seen for each day, cheapest first.

American Airlines
Depart10:17 Mon, Nov 16MYR → SDF 2h 33m · 1 stop
$262one way, per person
View deal
See every date in November 2026 →

Plan the rest of your trip to Louisville

Where to stay, what to do and getting around, from our travel partners.

About flights from Myrtle Beach to Louisville

Myrtle Beach (MYR) and Louisville (SDF) are about 800 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 2h 33m. Over the next few months, one-way fares start from $262, and November 2026 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Myrtle Beach to Louisville?

The cheapest one-way fare we've seen recently is $262 with American Airlines, departing Monday, November 16, 2026.

What is the cheapest month to fly from Myrtle Beach to Louisville?

November 2026 currently has the lowest fares, from $262 one way.

Are there direct flights from Myrtle Beach to Louisville?

We haven't seen direct fares recently, so most journeys include at least one stop.

How long is the flight from Myrtle Beach to Louisville?

The quickest journey we've seen takes about 2h 33m. Myrtle Beach and Louisville are around 800 km apart.

Which airlines fly from Myrtle Beach to Louisville?

Recent fares on this route were with American Airlines.

More cheap flights from Myrtle Beach

Compare flights to Louisville from other cities →