American AirlinesDepart08:00
Fri, Nov 13PDX → GSP
7h 05m · 1 stop
$374one way, per person
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- Cheapest fare
- $374
- Cheapest month
- November
- Direct flights
- Not recently
- Quickest trip
- 6h 07m
American Airlines · Fri, Nov 13
from $374
Usually 1+ stop
3,580 km
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Cheapest month to fly from Portland to Greenville
Lowest one-way fare per person in each month. Choose a month to see every date.
Cheapest dates in November 2026
The lowest fares we've seen for each day, cheapest first.
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About flights from Portland to Greenville
Portland (PDX) and Greenville (GSP) are about 3,580 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 6h 07m. Over the next few months, one-way fares start from $374, and November 2026 is currently the cheapest month to fly.
These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.
Frequently asked questions
How much is a flight from Portland to Greenville?
The cheapest one-way fare we've seen recently is $374 with American Airlines, departing Friday, November 13, 2026.
What is the cheapest month to fly from Portland to Greenville?
November 2026 currently has the lowest fares, from $374 one way.
Are there direct flights from Portland to Greenville?
We haven't seen direct fares recently, so most journeys include at least one stop.
How long is the flight from Portland to Greenville?
The quickest journey we've seen takes about 6h 07m. Portland and Greenville are around 3,580 km apart.
Which airlines fly from Portland to Greenville?
Recent fares on this route were with American Airlines.
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