Cheap flights from Quito to Santiago

One-way fares from $288 · UIO → SCL · prices found by travellers in the last 48 hours

Compare all dates Santiago → Quito
Cheapest fare
$288

JetSmart · Wed, Jan 13

Cheapest month
January

from $288

Direct flights
Not recently

Usually 1+ stop

Quickest trip
5h 46m

3,790 km

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Cheapest month to fly from Quito to Santiago

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 $345
  2. December 2026 $311
  3. January 2027 Cheapest $288

Cheapest dates in January 2027

The lowest fares we've seen for each day, cheapest first.

JetSmart
Depart16:50 Wed, Jan 13UIO → SCL 5h 48m · 1 stop
$288one way, per person
View deal
JetSmart
Depart16:50 Sun, Jan 10UIO → SCL 5h 48m · 1 stop
$328one way, per person
View deal
See every date in January 2027 →

Plan the rest of your trip to Santiago

Where to stay, what to do and getting around, from our travel partners.

Where to stay

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Things to do

Things to do in SantiagoTours, attractions and day trips on Klook Explore →

Getting around

Airport transfer in SantiagoPre-book a driver to meet you at arrivals, with Kiwitaxi Book a transfer → Car hire in SantiagoCompare rental cars from major brands on EconomyBookings Compare cars →

Stay connected

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About flights from Quito to Santiago

Quito (UIO) and Santiago (SCL) are about 3,790 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 5h 46m. Over the next few months, one-way fares start from $288, and January 2027 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Quito to Santiago?

The cheapest one-way fare we've seen recently is $288 with JetSmart, departing Wednesday, January 13, 2027. Over the coming months, the lowest fare in each month ranges from $288 to $345.

What is the cheapest month to fly from Quito to Santiago?

January 2027 currently has the lowest fares, from $288 one way.

Are there direct flights from Quito to Santiago?

We haven't seen direct fares recently, so most journeys include at least one stop.

How long is the flight from Quito to Santiago?

The quickest journey we've seen takes about 5h 46m. Quito and Santiago are around 3,790 km apart.

Which airlines fly from Quito to Santiago?

Recent fares on this route were with LATAM Airlines Group and JetSmart.

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