Cheap flights from Rome to Mytilene

One-way fares from €134 · ROM → MJT · prices found by travellers in the last 48 hours

Cheapest fare
€134

ALPAVIA · Wed, 9 Dec

Cheapest month
December

from €134

Direct flights
Not recently

Usually 1+ stop

Quickest trip
3h 45m

1,230 km

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Cheapest month to fly from Rome to Mytilene

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. December 2026 Cheapest €134

Cheapest dates in December 2026

The lowest fares we've seen for each day, cheapest first.

ALPAVIA
Depart06:10 Wed, 9 DecCIA → MJT 3h 45m · 2 stops
€134one way, per person
View deal
See every date in December 2026 →

Plan the rest of your trip to Mytilene

Where to stay, what to do and getting around, from our travel partners.

About flights from Rome to Mytilene

Rome (ROM) and Mytilene (MJT) are about 1,230 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 3h 45m. Over the next few months, one-way fares start from €134, and December 2026 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Rome to Mytilene?

The cheapest one-way fare we've seen recently is €134 with ALPAVIA, departing Wednesday, 9 December 2026.

What is the cheapest month to fly from Rome to Mytilene?

December 2026 currently has the lowest fares, from €134 one way.

Are there direct flights from Rome to Mytilene?

We haven't seen direct fares recently, so most journeys include at least one stop.

How long is the flight from Rome to Mytilene?

The quickest journey we've seen takes about 3h 45m. Rome and Mytilene are around 1,230 km apart.

Which airlines fly from Rome to Mytilene?

Recent fares on this route were with ALPAVIA.

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