Aerolineas ArgentinasDepart09:40
Tue, Nov 10SFN → SDE
2h 50m · 1 stop
$127one way, per person
View deal
- Cheapest fare
- $127
- Cheapest month
- November
- Direct flights
- Not recently
- Quickest trip
- 2h 50m
Aerolineas Argentinas · Tue, Nov 10
from $127
Usually 1+ stop
540 km
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Cheapest month to fly from Santa Fe to Santiago Del Estero
Lowest one-way fare per person in each month. Choose a month to see every date.
Cheapest dates in November 2026
The lowest fares we've seen for each day, cheapest first.
Aerolineas ArgentinasPlan the rest of your trip to Santiago Del Estero
Where to stay, what to do and getting around, from our travel partners.
About flights from Santa Fe to Santiago Del Estero
Santa Fe (SFN) and Santiago Del Estero (SDE) are about 540 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 2h 50m. Over the next few months, one-way fares start from $127, and November 2026 is currently the cheapest month to fly.
These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.
Frequently asked questions
How much is a flight from Santa Fe to Santiago Del Estero?
The cheapest one-way fare we've seen recently is $127 with Aerolineas Argentinas, departing Tuesday, November 10, 2026.
What is the cheapest month to fly from Santa Fe to Santiago Del Estero?
November 2026 currently has the lowest fares, from $127 one way.
Are there direct flights from Santa Fe to Santiago Del Estero?
We haven't seen direct fares recently, so most journeys include at least one stop.
How long is the flight from Santa Fe to Santiago Del Estero?
The quickest journey we've seen takes about 2h 50m. Santa Fe and Santiago Del Estero are around 540 km apart.
Which airlines fly from Santa Fe to Santiago Del Estero?
Recent fares on this route were with Aerolineas Argentinas.
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