United AirlinesDepart18:50
Sat, Nov 21STL → VVI
11h 53m · 2 stops
$539one way, per person
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- Cheapest fare
- $539
- Cheapest month
- November
- Direct flights
- Not recently
- Quickest trip
- 11h 53m
United Airlines · Sat, Nov 21
from $539
Usually 1+ stop
6,880 km
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Cheapest month to fly from St Louis to Santa Cruz
Lowest one-way fare per person in each month. Choose a month to see every date.
Cheapest dates in November 2026
The lowest fares we've seen for each day, cheapest first.
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Where to stay, what to do and getting around, from our travel partners.
About flights from St Louis to Santa Cruz
St Louis (STL) and Santa Cruz (SRZ) are about 6,880 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 11h 53m. Over the next few months, one-way fares start from $539, and November 2026 is currently the cheapest month to fly.
These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.
Frequently asked questions
How much is a flight from St Louis to Santa Cruz?
The cheapest one-way fare we've seen recently is $539 with United Airlines, departing Saturday, November 21, 2026.
What is the cheapest month to fly from St Louis to Santa Cruz?
November 2026 currently has the lowest fares, from $539 one way.
Are there direct flights from St Louis to Santa Cruz?
We haven't seen direct fares recently, so most journeys include at least one stop.
How long is the flight from St Louis to Santa Cruz?
The quickest journey we've seen takes about 11h 53m. St Louis and Santa Cruz are around 6,880 km apart.
Which airlines fly from St Louis to Santa Cruz?
Recent fares on this route were with United Airlines.
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