Cheap flights from Cali to Medellin

One-way fares from $38 · CLO → MDE · prices found by travellers in the last 48 hours

Cheapest fare
$38

LATAM Airlines Group · Sat, Nov 7

Cheapest month
November

from $38

Direct flights
Yes

JetSmart

Flight time
0h 56m

330 km

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Cheapest month to fly from Cali to Medellin

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 Cheapest $38

Cheapest dates in November 2026

The lowest fares we've seen for each day, cheapest first.

avianca airlines
Depart12:15 Sat, Nov 7CLO → MDE 2h 10m · 1 stop
$38one way, per person
View deal
JetSmart
Depart13:56 Thu, Nov 12CLO → MDE 0h 56m · Direct
$49one way, per person
View deal
See every date in November 2026 →

Plan the rest of your trip to Medellin

Where to stay, what to do and getting around, from our travel partners.

About flights from Cali to Medellin

Cali (CLO) and Medellin (MDE) are about 330 km apart. Direct flights take around 0h 56m, and recent direct fares were with JetSmart. Over the next few months, one-way fares start from $38, and November 2026 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Cali to Medellin?

The cheapest one-way fare we've seen recently is $38 with LATAM Airlines Group, departing Saturday, November 7, 2026.

What is the cheapest month to fly from Cali to Medellin?

November 2026 currently has the lowest fares, from $38 one way.

Are there direct flights from Cali to Medellin?

Yes. Recent direct fares were with JetSmart.

How long is the flight from Cali to Medellin?

A direct flight takes about 0h 56m. Cali and Medellin are around 330 km apart.

Which airlines fly from Cali to Medellin?

Recent fares on this route were with LATAM Airlines Group, avianca airlines and JetSmart.

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