Cheap flights from Medellin to Cali

One-way fares from $46 · MDE → CLO · prices found by travellers in the last 48 hours

Compare all dates Cali → Medellin
Cheapest fare
$46

JetSmart · Thu, Nov 12

Cheapest month
November

from $46

Direct flights
Yes

JetSmart

Flight time
1h 09m

330 km

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Cheapest month to fly from Medellin to Cali

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 Cheapest $46
  2. December 2026 $75

Cheapest dates in November 2026

The lowest fares we've seen for each day, cheapest first.

JetSmart
Depart05:35 Thu, Nov 12MDE → CLO 1h 09m · Direct
$46one way, per person
View deal
JetSmart
Depart13:55 Wed, Nov 11MDE → CLO 1h 09m · Direct
$48one way, per person
View deal
JetSmart
Depart05:30 Fri, Nov 13MDE → CLO 1h 09m · Direct
$51one way, per person
View deal
See every date in November 2026 →

Plan the rest of your trip to Cali

Where to stay, what to do and getting around, from our travel partners.

Where to stay

Hotels in CaliCompare places to stay on Booking.com Find hotels →

Things to do

Things to do in CaliTours, attractions and day trips on Klook Explore →

Getting around

Airport transfer in CaliPre-book a driver to meet you at arrivals, with Kiwitaxi Book a transfer → Car hire in CaliCompare rental cars from major brands on EconomyBookings Compare cars →

About flights from Medellin to Cali

Medellin (MDE) and Cali (CLO) are about 330 km apart. Direct flights take around 1h 09m, and recent direct fares were with JetSmart. Over the next few months, one-way fares start from $46, and November 2026 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Medellin to Cali?

The cheapest one-way fare we've seen recently is $46 with JetSmart, departing Thursday, November 12, 2026. Over the coming months, the lowest fare in each month ranges from $46 to $75.

What is the cheapest month to fly from Medellin to Cali?

November 2026 currently has the lowest fares, from $46 one way.

Are there direct flights from Medellin to Cali?

Yes. Recent direct fares were with JetSmart.

How long is the flight from Medellin to Cali?

A direct flight takes about 1h 09m. Medellin and Cali are around 330 km apart.

Which airlines fly from Medellin to Cali?

Recent fares on this route were with JetSmart.

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