avianca airlinesDepart08:50
Sun, Nov 8CLO → PTY
2h 55m · 1 stop
$253one way, per person
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- Cheapest fare
- $253
- Cheapest month
- November
- Direct flights
- Not recently
- Quickest trip
- 2h 45m
avianca airlines · Mon, Nov 9
from $253
Usually 1+ stop
700 km
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Cheapest month to fly from Cali to Panama City
Lowest one-way fare per person in each month. Choose a month to see every date.
Cheapest dates in November 2026
The lowest fares we've seen for each day, cheapest first.
avianca airlinesavianca airlinesDepart12:15
Mon, Nov 9CLO → PTY
2h 50m · 1 stop
$253one way, per person
View deal
avianca airlinesDepart18:40
Wed, Nov 11CLO → PTY
2h 45m · 1 stop
$256one way, per person
View deal
avianca airlinesDepart10:30
Thu, Nov 12CLO → PTY
2h 55m · 1 stop
$256one way, per person
View deal
avianca airlinesDepart10:30
Sat, Nov 7CLO → PTY
2h 55m · 1 stop
$258one way, per person
View deal
avianca airlinesDepart22:15
Tue, Nov 3CLO → PTY
2h 55m · 1 stop
$262one way, per person
View deal
Plan the rest of your trip to Panama City
Where to stay, what to do and getting around, from our travel partners.
About flights from Cali to Panama City
Cali (CLO) and Panama City (PTY) are about 700 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 2h 45m. Over the next few months, one-way fares start from $253, and November 2026 is currently the cheapest month to fly.
These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.
Frequently asked questions
How much is a flight from Cali to Panama City?
The cheapest one-way fare we've seen recently is $253 with avianca airlines, departing Monday, November 9, 2026.
What is the cheapest month to fly from Cali to Panama City?
November 2026 currently has the lowest fares, from $253 one way.
Are there direct flights from Cali to Panama City?
We haven't seen direct fares recently, so most journeys include at least one stop.
How long is the flight from Cali to Panama City?
The quickest journey we've seen takes about 2h 45m. Cali and Panama City are around 700 km apart.
Which airlines fly from Cali to Panama City?
Recent fares on this route were with avianca airlines.