Cheap flights from Cali to Santiago

One-way fares from $270 · CLO → SCL · prices found by travellers in the last 48 hours

Cheapest fare
$270

JetSmart · Mon, Nov 30

Cheapest month
November

from $270

Direct flights
Yes

JetSmart

Flight time
5h 39m

4,150 km

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Cheapest month to fly from Cali to Santiago

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 Cheapest $270

Cheapest dates in November 2026

The lowest fares we've seen for each day, cheapest first.

JetSmart
Depart21:35 Mon, Nov 30CLO → SCL 5h 39m · Direct
$270one way, per person
View deal
See every date in November 2026 →

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About flights from Cali to Santiago

Cali (CLO) and Santiago (SCL) are about 4,150 km apart. Direct flights take around 5h 39m, and recent direct fares were with JetSmart. Over the next few months, one-way fares start from $270, and November 2026 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Cali to Santiago?

The cheapest one-way fare we've seen recently is $270 with JetSmart, departing Monday, November 30, 2026.

What is the cheapest month to fly from Cali to Santiago?

November 2026 currently has the lowest fares, from $270 one way.

Are there direct flights from Cali to Santiago?

Yes. Recent direct fares were with JetSmart.

How long is the flight from Cali to Santiago?

A direct flight takes about 5h 39m. Cali and Santiago are around 4,150 km apart.

Which airlines fly from Cali to Santiago?

Recent fares on this route were with JetSmart.

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