- Cheapest fare
- $270
- Cheapest month
- November
- Direct flights
- Yes
- Flight time
- 5h 39m
JetSmart · Mon, Nov 30
from $270
JetSmart
4,150 km
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Cheapest month to fly from Cali to Santiago
Lowest one-way fare per person in each month. Choose a month to see every date.
Cheapest dates in November 2026
The lowest fares we've seen for each day, cheapest first.
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Getting around
About flights from Cali to Santiago
Cali (CLO) and Santiago (SCL) are about 4,150 km apart. Direct flights take around 5h 39m, and recent direct fares were with JetSmart. Over the next few months, one-way fares start from $270, and November 2026 is currently the cheapest month to fly.
These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.
Frequently asked questions
How much is a flight from Cali to Santiago?
The cheapest one-way fare we've seen recently is $270 with JetSmart, departing Monday, November 30, 2026.
What is the cheapest month to fly from Cali to Santiago?
November 2026 currently has the lowest fares, from $270 one way.
Are there direct flights from Cali to Santiago?
Yes. Recent direct fares were with JetSmart.
How long is the flight from Cali to Santiago?
A direct flight takes about 5h 39m. Cali and Santiago are around 4,150 km apart.
Which airlines fly from Cali to Santiago?
Recent fares on this route were with JetSmart.