Cheap flights from Cali to Santo Domingo

One-way fares from $333 · CLO → SDQ · prices found by travellers in the last 48 hours

Cheapest fare
$333

avianca airlines · Thu, Dec 31

Cheapest month
December

from $333

Direct flights
Not recently

Usually 1+ stop

Quickest trip
4h 34m

1,820 km

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Cheapest month to fly from Cali to Santo Domingo

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. December 2026 Cheapest $333

Cheapest dates in December 2026

The lowest fares we've seen for each day, cheapest first.

avianca airlines
Depart08:00 Thu, Dec 31CLO → SDQ 4h 34m · 2 stops
$333one way, per person
View deal
See every date in December 2026 →

Plan the rest of your trip to Santo Domingo

Where to stay, what to do and getting around, from our travel partners.

About flights from Cali to Santo Domingo

Cali (CLO) and Santo Domingo (SDQ) are about 1,820 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 4h 34m. Over the next few months, one-way fares start from $333, and December 2026 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Cali to Santo Domingo?

The cheapest one-way fare we've seen recently is $333 with avianca airlines, departing Thursday, December 31, 2026.

What is the cheapest month to fly from Cali to Santo Domingo?

December 2026 currently has the lowest fares, from $333 one way.

Are there direct flights from Cali to Santo Domingo?

We haven't seen direct fares recently, so most journeys include at least one stop.

How long is the flight from Cali to Santo Domingo?

The quickest journey we've seen takes about 4h 34m. Cali and Santo Domingo are around 1,820 km apart.

Which airlines fly from Cali to Santo Domingo?

Recent fares on this route were with avianca airlines.

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