Cheap flights from Cusco to Santiago

One-way fares from $96 · CUZ → SCL · prices found by travellers in the last 48 hours

Compare all dates Santiago → Cusco
Cheapest fare
$96

Sky Airline · Thu, Feb 11

Cheapest month
February

from $96

Direct flights
Yes

Sky Airline

Flight time
3h 29m

2,220 km

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Cheapest month to fly from Cusco to Santiago

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 $132
  2. December 2026 $104
  3. January 2027 $166
  4. February 2027 Cheapest $96
  5. March 2027 $100

Cheapest dates in February 2027

The lowest fares we've seen for each day, cheapest first.

Sky Airline
Depart18:25 Thu, Feb 11CUZ → SCL 3h 29m · Direct
$96one way, per person
View deal
JetSmart
Depart20:50 Fri, Feb 12CUZ → SCL 5h 13m · 1 stop
$160one way, per person
View deal
See every date in February 2027 →

Plan the rest of your trip to Santiago

Where to stay, what to do and getting around, from our travel partners.

Where to stay

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Things to do

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Getting around

Airport transfer in SantiagoPre-book a driver to meet you at arrivals, with Kiwitaxi Book a transfer → Car hire in SantiagoCompare rental cars from major brands on EconomyBookings Compare cars →

Stay connected

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About flights from Cusco to Santiago

Cusco (CUZ) and Santiago (SCL) are about 2,220 km apart. Direct flights take around 3h 29m, and recent direct fares were with Sky Airline. Over the next few months, one-way fares start from $96, and February 2027 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Cusco to Santiago?

The cheapest one-way fare we've seen recently is $96 with Sky Airline, departing Thursday, February 11, 2027. Over the coming months, the lowest fare in each month ranges from $96 to $166.

What is the cheapest month to fly from Cusco to Santiago?

February 2027 currently has the lowest fares, from $96 one way.

Are there direct flights from Cusco to Santiago?

Yes. Recent direct fares were with Sky Airline.

How long is the flight from Cusco to Santiago?

A direct flight takes about 3h 29m. Cusco and Santiago are around 2,220 km apart.

Which airlines fly from Cusco to Santiago?

Recent fares on this route were with Sky Airline and JetSmart.

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