Sky AirlineDepart15:10
Mon, Mar 22SCL → CUZ
3h 30m · Direct
$110one way, per person
View deal
- Cheapest fare
- $110
- Cheapest month
- March
- Direct flights
- Yes
- Flight time
- 3h 30m
Sky Airline · Mon, Mar 22
from $110
LATAM Airlines Group and Sky Airline
2,220 km
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Cheapest month to fly from Santiago to Cusco
Lowest one-way fare per person in each month. Choose a month to see every date.
Cheapest dates in March 2027
The lowest fares we've seen for each day, cheapest first.
See every date in March 2027 →
Plan the rest of your trip to Cusco
Where to stay, what to do and getting around, from our travel partners.
Getting around
About flights from Santiago to Cusco
Santiago (SCL) and Cusco (CUZ) are about 2,220 km apart. Direct flights take around 3h 30m, and recent direct fares were with LATAM Airlines Group and Sky Airline. Over the next few months, one-way fares start from $110, and March 2027 is currently the cheapest month to fly.
These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.
Frequently asked questions
How much is a flight from Santiago to Cusco?
The cheapest one-way fare we've seen recently is $110 with Sky Airline, departing Monday, March 22, 2027. Over the coming months, the lowest fare in each month ranges from $110 to $130.
What is the cheapest month to fly from Santiago to Cusco?
March 2027 currently has the lowest fares, from $110 one way.
Are there direct flights from Santiago to Cusco?
Yes. Recent direct fares were with LATAM Airlines Group and Sky Airline.
How long is the flight from Santiago to Cusco?
A direct flight takes about 3h 30m. Santiago and Cusco are around 2,220 km apart.
Which airlines fly from Santiago to Cusco?
Recent fares on this route were with Sky Airline and LATAM Airlines Group.
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