Cheap flights from Guatemala City to Panama City

One-way fares from $303 · GUA → PTY · prices found by travellers in the last 48 hours

Compare all dates Panama City → Guatemala City
Cheapest fare
$303

avianca airlines · Wed, Nov 4

Cheapest month
November

from $303

Direct flights
Not recently

Usually 1+ stop

Quickest trip
4h 55m

1,350 km

Get a price alert

We'll email you when Guatemala City → Panama City drops to your price. It's free, and you can stop any time.

Today's cheapest fare is $303. We'll send one email to confirm. See our privacy policy.

Cheapest month to fly from Guatemala City to Panama City

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 Cheapest $303
  2. December 2026 $318
  3. February 2027 $332
  4. April 2027 $304

Plan the rest of your trip to Panama City

Where to stay, what to do and getting around, from our travel partners.

Where to stay

Hotels in Panama CityCompare places to stay on Booking.com Find hotels →

Things to do

Things to do in Panama CityTours, attractions and day trips on Klook Explore →

Getting around

Airport transfer in Panama CityPre-book a driver to meet you at arrivals, with Kiwitaxi Book a transfer → Car hire in Panama CityCompare rental cars from major brands on EconomyBookings Compare cars →

About flights from Guatemala City to Panama City

Guatemala City (GUA) and Panama City (PTY) are about 1,350 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 4h 55m. Over the next few months, one-way fares start from $303, and November 2026 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Guatemala City to Panama City?

The cheapest one-way fare we've seen recently is $303 with avianca airlines, departing Wednesday, November 4, 2026. Over the coming months, the lowest fare in each month ranges from $303 to $332.

What is the cheapest month to fly from Guatemala City to Panama City?

November 2026 currently has the lowest fares, from $303 one way.

Are there direct flights from Guatemala City to Panama City?

We haven't seen direct fares recently, so most journeys include at least one stop.

How long is the flight from Guatemala City to Panama City?

The quickest journey we've seen takes about 4h 55m. Guatemala City and Panama City are around 1,350 km apart.

Which airlines fly from Guatemala City to Panama City?

Recent fares on this route were with avianca airlines.

More cheap flights from Guatemala City

Compare flights to Panama City from other cities →