Cheap flights from Panama City to Guatemala City

One-way fares from $291 · PTY → GUA · prices found by travellers in the last 48 hours

Compare all dates Guatemala City → Panama City
Cheapest fare
$291

avianca airlines El Salvador · Tue, Jan 5

Cheapest month
January

from $291

Direct flights
Yes

Copa Airlines

Flight time
2h 21m

1,350 km

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Cheapest month to fly from Panama City to Guatemala City

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 $331
  2. January 2027 Cheapest $291
  3. February 2027 $310

Cheapest dates in January 2027

The lowest fares we've seen for each day, cheapest first.

avianca airlines El Salvador
Depart05:30 Tue, Jan 5PTY → GUA 2h 45m · 1 stop
$291one way, per person
View deal
See every date in January 2027 →

Plan the rest of your trip to Guatemala City

Where to stay, what to do and getting around, from our travel partners.

Where to stay

Hotels in Guatemala CityCompare places to stay on Booking.com Find hotels →

Things to do

Things to do in Guatemala CityTours, attractions and day trips on Klook Explore →

Getting around

Airport transfer in Guatemala CityPre-book a driver to meet you at arrivals, with Kiwitaxi Book a transfer → Car hire in Guatemala CityCompare rental cars from major brands on EconomyBookings Compare cars →

About flights from Panama City to Guatemala City

Panama City (PTY) and Guatemala City (GUA) are about 1,350 km apart. Direct flights take around 2h 21m, and recent direct fares were with Copa Airlines. Over the next few months, one-way fares start from $291, and January 2027 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Panama City to Guatemala City?

The cheapest one-way fare we've seen recently is $291 with avianca airlines El Salvador, departing Tuesday, January 5, 2027. Over the coming months, the lowest fare in each month ranges from $291 to $331.

What is the cheapest month to fly from Panama City to Guatemala City?

January 2027 currently has the lowest fares, from $291 one way.

Are there direct flights from Panama City to Guatemala City?

Yes. Recent direct fares were with Copa Airlines.

How long is the flight from Panama City to Guatemala City?

A direct flight takes about 2h 21m. Panama City and Guatemala City are around 1,350 km apart.

Which airlines fly from Panama City to Guatemala City?

Recent fares on this route were with Copa Airlines, avianca airlines El Salvador and avianca airlines.

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