Cheap flights from Guatemala City to Santiago

One-way fares from $368 · GUA → SCL · prices found by travellers in the last 48 hours

Cheapest fare
$368

Volaris · Tue, Dec 29

Cheapest month
December

from $368

Direct flights
Not recently

Usually 1+ stop

Quickest trip
10h 25m

5,750 km

Get a price alert

We'll email you when Guatemala City → Santiago drops to your price. It's free, and you can stop any time.

Today's cheapest fare is $368. We'll send one email to confirm. See our privacy policy.

Cheapest month to fly from Guatemala City to Santiago

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 $513
  2. December 2026 Cheapest $368

Cheapest dates in December 2026

The lowest fares we've seen for each day, cheapest first.

Volaris
Depart08:55 Tue, Dec 29GUA → SCL 10h 25m · 1 stop
$368one way, per person
View deal
See every date in December 2026 →

Plan the rest of your trip to Santiago

Where to stay, what to do and getting around, from our travel partners.

About flights from Guatemala City to Santiago

Guatemala City (GUA) and Santiago (SCL) are about 5,750 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 10h 25m. Over the next few months, one-way fares start from $368, and December 2026 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Guatemala City to Santiago?

The cheapest one-way fare we've seen recently is $368 with Volaris, departing Tuesday, December 29, 2026. Over the coming months, the lowest fare in each month ranges from $368 to $513.

What is the cheapest month to fly from Guatemala City to Santiago?

December 2026 currently has the lowest fares, from $368 one way.

Are there direct flights from Guatemala City to Santiago?

We haven't seen direct fares recently, so most journeys include at least one stop.

How long is the flight from Guatemala City to Santiago?

The quickest journey we've seen takes about 10h 25m. Guatemala City and Santiago are around 5,750 km apart.

Which airlines fly from Guatemala City to Santiago?

Recent fares on this route were with Volaris.

More cheap flights from Guatemala City

Compare flights to Santiago from other cities →