Cheap flights from Santiago to Guatemala City

One-way fares from $307 · SCL → GUA · prices found by travellers in the last 48 hours

Compare all dates Guatemala City → Santiago
Cheapest fare
$307

JetSmart · Thu, Jan 21

Cheapest month
January

from $307

Direct flights
Not recently

Usually 1+ stop

Quickest trip
9h 12m

5,750 km

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Cheapest month to fly from Santiago to Guatemala City

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. December 2026 $335
  2. January 2027 Cheapest $307
  3. April 2027 $316

Cheapest dates in January 2027

The lowest fares we've seen for each day, cheapest first.

JetSmart
Depart12:32 Thu, Jan 21SCL → GUA 11h 53m · 2 stops
$307one way, per person
View deal
Sky Airline
Depart13:38 Wed, Jan 20SCL → GUA 11h 52m · 2 stops
$323one way, per person
View deal
See every date in January 2027 →

Plan the rest of your trip to Guatemala City

Where to stay, what to do and getting around, from our travel partners.

Where to stay

Hotels in Guatemala CityCompare places to stay on Booking.com Find hotels →

Things to do

Things to do in Guatemala CityTours, attractions and day trips on Klook Explore →

Getting around

Airport transfer in Guatemala CityPre-book a driver to meet you at arrivals, with Kiwitaxi Book a transfer → Car hire in Guatemala CityCompare rental cars from major brands on EconomyBookings Compare cars →

About flights from Santiago to Guatemala City

Santiago (SCL) and Guatemala City (GUA) are about 5,750 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 9h 12m. Over the next few months, one-way fares start from $307, and January 2027 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Santiago to Guatemala City?

The cheapest one-way fare we've seen recently is $307 with JetSmart, departing Thursday, January 21, 2027. Over the coming months, the lowest fare in each month ranges from $307 to $335.

What is the cheapest month to fly from Santiago to Guatemala City?

January 2027 currently has the lowest fares, from $307 one way.

Are there direct flights from Santiago to Guatemala City?

We haven't seen direct fares recently, so most journeys include at least one stop.

How long is the flight from Santiago to Guatemala City?

The quickest journey we've seen takes about 9h 12m. Santiago and Guatemala City are around 5,750 km apart.

Which airlines fly from Santiago to Guatemala City?

Recent fares on this route were with Copa Airlines, JetSmart and Sky Airline.

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