Cheap flights from Guayaquil to Medellin

One-way fares from $185 · GYE → MDE · prices found by travellers in the last 48 hours

Compare all dates Medellin → Guayaquil
Cheapest fare
$185

avianca airlines · Wed, Nov 25

Cheapest month
November

from $185

Direct flights
Yes

avianca airlines

Flight time
1h 45m

1,050 km

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Cheapest month to fly from Guayaquil to Medellin

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 Cheapest $185
  2. December 2026 $197

Cheapest dates in November 2026

The lowest fares we've seen for each day, cheapest first.

avianca airlines
Depart13:35 Wed, Nov 25GYE → MDE 1h 45m · Direct
$185one way, per person
View deal
Copa Airlines
Depart05:54 Sat, Nov 7GYE → MDE 3h 35m · 1 stop
$195one way, per person
View deal
See every date in November 2026 →

Plan the rest of your trip to Medellin

Where to stay, what to do and getting around, from our travel partners.

Where to stay

Hotels in MedellinCompare places to stay on Booking.com Find hotels →

Things to do

Things to do in MedellinTours, attractions and day trips on Klook Explore →

Getting around

Airport transfer in MedellinPre-book a driver to meet you at arrivals, with Kiwitaxi Book a transfer → Car hire in MedellinCompare rental cars from major brands on EconomyBookings Compare cars →

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About flights from Guayaquil to Medellin

Guayaquil (GYE) and Medellin (MDE) are about 1,050 km apart. Direct flights take around 1h 45m, and recent direct fares were with avianca airlines. Over the next few months, one-way fares start from $185, and November 2026 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Guayaquil to Medellin?

The cheapest one-way fare we've seen recently is $185 with avianca airlines, departing Wednesday, November 25, 2026. Over the coming months, the lowest fare in each month ranges from $185 to $197.

What is the cheapest month to fly from Guayaquil to Medellin?

November 2026 currently has the lowest fares, from $185 one way.

Are there direct flights from Guayaquil to Medellin?

Yes. Recent direct fares were with avianca airlines.

How long is the flight from Guayaquil to Medellin?

A direct flight takes about 1h 45m. Guayaquil and Medellin are around 1,050 km apart.

Which airlines fly from Guayaquil to Medellin?

Recent fares on this route were with avianca airlines and Copa Airlines.

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