Avelo AirlinesDepart14:16
Thu, Nov 12TYS → MYR
4h 05m · 1 stop
$141one way, per person
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- Cheapest fare
- $141
- Cheapest month
- November
- Direct flights
- Not recently
- Quickest trip
- 4h 05m
Avelo Airlines · Thu, Nov 12
from $141
Usually 1+ stop
520 km
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Cheapest month to fly from Knoxville to Myrtle Beach
Lowest one-way fare per person in each month. Choose a month to see every date.
Cheapest dates in November 2026
The lowest fares we've seen for each day, cheapest first.
Avelo AirlinesPlan the rest of your trip to Myrtle Beach
Where to stay, what to do and getting around, from our travel partners.
About flights from Knoxville to Myrtle Beach
Knoxville (TYS) and Myrtle Beach (MYR) are about 520 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 4h 05m. Over the next few months, one-way fares start from $141, and November 2026 is currently the cheapest month to fly.
These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.
Frequently asked questions
How much is a flight from Knoxville to Myrtle Beach?
The cheapest one-way fare we've seen recently is $141 with Avelo Airlines, departing Thursday, November 12, 2026.
What is the cheapest month to fly from Knoxville to Myrtle Beach?
November 2026 currently has the lowest fares, from $141 one way.
Are there direct flights from Knoxville to Myrtle Beach?
We haven't seen direct fares recently, so most journeys include at least one stop.
How long is the flight from Knoxville to Myrtle Beach?
The quickest journey we've seen takes about 4h 05m. Knoxville and Myrtle Beach are around 520 km apart.
Which airlines fly from Knoxville to Myrtle Beach?
Recent fares on this route were with Avelo Airlines.
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