Cheap flights from Madrid to Santa Cruz

One-way fares from €360 · MAD → SRZ · prices found by travellers in the last 48 hours

Compare all dates Santa Cruz → Madrid
Cheapest fare
€360

avianca airlines · Thu, 4 Feb

Cheapest month
February

from €360

Direct flights
Yes

Air Europa

Flight time
11h 20m

8,920 km

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Cheapest month to fly from Madrid to Santa Cruz

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 €585
  2. December 2026 €609
  3. January 2027 €470
  4. February 2027 Cheapest €360
  5. May 2027 €360

Cheapest dates in February 2027

The lowest fares we've seen for each day, cheapest first.

avianca airlines
Depart10:10 Thu, 4 FebMAD → VVI 14h 30m · 1 stop
€360one way, per person
View deal
Air Europa
Depart23:35 Mon, 1 FebMAD → VVI 11h 20m · Direct
€563one way, per person
View deal
See every date in February 2027 →

Plan the rest of your trip to Santa Cruz

Where to stay, what to do and getting around, from our travel partners.

Where to stay

Hotels in Santa CruzCompare places to stay on Booking.com Find hotels →

Things to do

Things to do in Santa CruzTours, attractions and day trips on Klook Explore →

Getting around

Airport transfer in Santa CruzPre-book a driver to meet you at arrivals, with Kiwitaxi Book a transfer → Car hire in Santa CruzCompare rental cars from major brands on EconomyBookings Compare cars →

About flights from Madrid to Santa Cruz

Madrid (MAD) and Santa Cruz (SRZ) are about 8,920 km apart. Direct flights take around 11h 20m, and recent direct fares were with Air Europa. Over the next few months, one-way fares start from €360, and February 2027 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Madrid to Santa Cruz?

The cheapest one-way fare we've seen recently is €360 with avianca airlines, departing Thursday, 4 February 2027. Over the coming months, the lowest fare in each month ranges from €360 to €609.

What is the cheapest month to fly from Madrid to Santa Cruz?

February 2027 currently has the lowest fares, from €360 one way.

Are there direct flights from Madrid to Santa Cruz?

Yes. Recent direct fares were with Air Europa.

How long is the flight from Madrid to Santa Cruz?

A direct flight takes about 11h 20m. Madrid and Santa Cruz are around 8,920 km apart.

Which airlines fly from Madrid to Santa Cruz?

Recent fares on this route were with Air Europa, avianca airlines, Wizz Air Malta and Boliviana de Aviación.

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