Cheap flights from Santa Cruz to Madrid

One-way fares from $457 · SRZ → MAD · prices found by travellers in the last 48 hours

Cheapest fare
$457

Boliviana de Aviación · Sun, Nov 8

Cheapest month
November

from $457

Direct flights
Yes

Boliviana de Aviación

Flight time
10h 45m

8,920 km

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Cheapest month to fly from Santa Cruz to Madrid

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 Cheapest $457
  2. December 2026 $589
  3. January 2027 $732
  4. May 2027 $651

Cheapest dates in November 2026

The lowest fares we've seen for each day, cheapest first.

Boliviana de Aviación
Depart20:30 Sun, Nov 8VVI → MAD 10h 45m · Direct
$457one way, per person
View deal
avianca airlines
Depart03:45 Sat, Nov 7VVI → MAD 13h 30m · 1 stop
$496one way, per person
View deal
See every date in November 2026 →

Plan the rest of your trip to Madrid

Where to stay, what to do and getting around, from our travel partners.

About flights from Santa Cruz to Madrid

Santa Cruz (SRZ) and Madrid (MAD) are about 8,920 km apart. Direct flights take around 10h 45m, and recent direct fares were with Boliviana de Aviación. Over the next few months, one-way fares start from $457, and November 2026 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Santa Cruz to Madrid?

The cheapest one-way fare we've seen recently is $457 with Boliviana de Aviación, departing Sunday, November 8, 2026. Over the coming months, the lowest fare in each month ranges from $457 to $732.

What is the cheapest month to fly from Santa Cruz to Madrid?

November 2026 currently has the lowest fares, from $457 one way.

Are there direct flights from Santa Cruz to Madrid?

Yes. Recent direct fares were with Boliviana de Aviación.

How long is the flight from Santa Cruz to Madrid?

A direct flight takes about 10h 45m. Santa Cruz and Madrid are around 8,920 km apart.

Which airlines fly from Santa Cruz to Madrid?

Recent fares on this route were with Boliviana de Aviación and avianca airlines.

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