AeromexicoDepart08:50
Tue, Dec 8MEX → PTY
3h 56m · Direct
$180one way, per person
View deal
- Cheapest fare
- $180
- Cheapest month
- December
- Direct flights
- Yes
- Flight time
- 3h 51m
Aeromexico · Tue, Dec 8
from $180
Aeromexico
2,410 km
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Cheapest month to fly from Mexico City to Panama City
Lowest one-way fare per person in each month. Choose a month to see every date.
Cheapest dates in December 2026
The lowest fares we've seen for each day, cheapest first.
See every date in December 2026 →
Plan the rest of your trip to Panama City
Where to stay, what to do and getting around, from our travel partners.
About flights from Mexico City to Panama City
Mexico City (MEX) and Panama City (PTY) are about 2,410 km apart. Direct flights take around 3h 51m, and recent direct fares were with Aeromexico. Over the next few months, one-way fares start from $180, and December 2026 is currently the cheapest month to fly.
These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.
Frequently asked questions
How much is a flight from Mexico City to Panama City?
The cheapest one-way fare we've seen recently is $180 with Aeromexico, departing Tuesday, December 8, 2026. Over the coming months, the lowest fare in each month ranges from $180 to $279.
What is the cheapest month to fly from Mexico City to Panama City?
December 2026 currently has the lowest fares, from $180 one way.
Are there direct flights from Mexico City to Panama City?
Yes. Recent direct fares were with Aeromexico.
How long is the flight from Mexico City to Panama City?
A direct flight takes about 3h 51m. Mexico City and Panama City are around 2,410 km apart.
Which airlines fly from Mexico City to Panama City?
Recent fares on this route were with Aeromexico and avianca airlines.
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