AeromexicoDepart14:49
Tue, Dec 29PTY → MEX
3h 51m · Direct
$284one way, per person
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- Cheapest fare
- $284
- Cheapest month
- December
- Direct flights
- Yes
- Flight time
- 3h 49m
Aeromexico · Tue, Dec 29
from $284
Aeromexico
2,410 km
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Cheapest month to fly from Panama City to Mexico City
Lowest one-way fare per person in each month. Choose a month to see every date.
Cheapest dates in December 2026
The lowest fares we've seen for each day, cheapest first.
See every date in December 2026 →Plan the rest of your trip to Mexico City
Where to stay, what to do and getting around, from our travel partners.
Getting around
About flights from Panama City to Mexico City
Panama City (PTY) and Mexico City (MEX) are about 2,410 km apart. Direct flights take around 3h 49m, and recent direct fares were with Aeromexico. Over the next few months, one-way fares start from $284, and December 2026 is currently the cheapest month to fly.
These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.
Frequently asked questions
How much is a flight from Panama City to Mexico City?
The cheapest one-way fare we've seen recently is $284 with Aeromexico, departing Tuesday, December 29, 2026. Over the coming months, the lowest fare in each month ranges from $284 to $307.
What is the cheapest month to fly from Panama City to Mexico City?
December 2026 currently has the lowest fares, from $284 one way.
Are there direct flights from Panama City to Mexico City?
Yes. Recent direct fares were with Aeromexico.
How long is the flight from Panama City to Mexico City?
A direct flight takes about 3h 49m. Panama City and Mexico City are around 2,410 km apart.
Which airlines fly from Panama City to Mexico City?
Recent fares on this route were with Aeromexico.
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