American AirlinesDepart15:58
Thu, Nov 12ECP → SDF
4h 33m · 1 stop
$334one way, per person
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- Cheapest fare
- $334
- Cheapest month
- November
- Direct flights
- Not recently
- Quickest trip
- 3h 08m
American Airlines · Thu, Nov 12
from $334
Usually 1+ stop
900 km
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Cheapest month to fly from Panama City to Louisville
Lowest one-way fare per person in each month. Choose a month to see every date.
Cheapest dates in November 2026
The lowest fares we've seen for each day, cheapest first.
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Where to stay, what to do and getting around, from our travel partners.
About flights from Panama City to Louisville
Panama City (ECP) and Louisville (SDF) are about 900 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 3h 08m. Over the next few months, one-way fares start from $334, and November 2026 is currently the cheapest month to fly.
These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.
Frequently asked questions
How much is a flight from Panama City to Louisville?
The cheapest one-way fare we've seen recently is $334 with American Airlines, departing Thursday, November 12, 2026.
What is the cheapest month to fly from Panama City to Louisville?
November 2026 currently has the lowest fares, from $334 one way.
Are there direct flights from Panama City to Louisville?
We haven't seen direct fares recently, so most journeys include at least one stop.
How long is the flight from Panama City to Louisville?
The quickest journey we've seen takes about 3h 08m. Panama City and Louisville are around 900 km apart.
Which airlines fly from Panama City to Louisville?
Recent fares on this route were with American Airlines.
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