American AirlinesDepart07:10
Fri, Nov 13ECP → MYR
3h 03m · 1 stop
$354one way, per person
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- Cheapest fare
- $354
- Cheapest month
- November
- Direct flights
- Not recently
- Quickest trip
- 2h 48m
American Airlines · Fri, Nov 13
from $354
Usually 1+ stop
750 km
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Cheapest month to fly from Panama City to Myrtle Beach
Lowest one-way fare per person in each month. Choose a month to see every date.
Cheapest dates in November 2026
The lowest fares we've seen for each day, cheapest first.
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Where to stay, what to do and getting around, from our travel partners.
About flights from Panama City to Myrtle Beach
Panama City (ECP) and Myrtle Beach (MYR) are about 750 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 2h 48m. Over the next few months, one-way fares start from $354, and November 2026 is currently the cheapest month to fly.
These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.
Frequently asked questions
How much is a flight from Panama City to Myrtle Beach?
The cheapest one-way fare we've seen recently is $354 with American Airlines, departing Friday, November 13, 2026.
What is the cheapest month to fly from Panama City to Myrtle Beach?
November 2026 currently has the lowest fares, from $354 one way.
Are there direct flights from Panama City to Myrtle Beach?
We haven't seen direct fares recently, so most journeys include at least one stop.
How long is the flight from Panama City to Myrtle Beach?
The quickest journey we've seen takes about 2h 48m. Panama City and Myrtle Beach are around 750 km apart.
Which airlines fly from Panama City to Myrtle Beach?
Recent fares on this route were with American Airlines.
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