Cheap flights from Santiago to Antofagasta

One-way fares from $30 · SCL → ANF · prices found by travellers in the last 48 hours

Compare all dates Antofagasta → Santiago
Cheapest fare
$30

JetSmart · Thu, Nov 12

Cheapest month
November

from $30

Direct flights
Yes

JetSmart and Sky Airline

Flight time
2h 00m

1,090 km

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Cheapest month to fly from Santiago to Antofagasta

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 Cheapest $30
  2. December 2026 $34

Cheapest dates in November 2026

The lowest fares we've seen for each day, cheapest first.

JetSmart
Depart20:22 Thu, Nov 12SCL → ANF 2h 04m · Direct
$30one way, per person
View deal
JetSmart
Depart13:11 Mon, Nov 30SCL → ANF 2h 04m · Direct
$35one way, per person
View deal
JetSmart
Depart07:45 Sat, Nov 21SCL → ANF 2h 04m · Direct
$36one way, per person
View deal
JetSmart
Depart21:19 Thu, Nov 5SCL → ANF 2h 04m · Direct
$40one way, per person
View deal
Sky Airline
Depart12:40 Sun, Nov 8SCL → ANF 2h 00m · Direct
$68one way, per person
View deal
JetSmart
Depart12:08 Mon, Nov 9SCL → ANF 2h 04m · Direct
$109one way, per person
View deal
See every date in November 2026 →

Plan the rest of your trip to Antofagasta

Where to stay, what to do and getting around, from our travel partners.

Where to stay

Hotels in AntofagastaCompare places to stay on Booking.com Find hotels →

Things to do

Things to do in AntofagastaTours, attractions and day trips on Klook Explore →

Getting around

Airport transfer in AntofagastaPre-book a driver to meet you at arrivals, with Kiwitaxi Book a transfer → Car hire in AntofagastaCompare rental cars from major brands on EconomyBookings Compare cars →

About flights from Santiago to Antofagasta

Santiago (SCL) and Antofagasta (ANF) are about 1,090 km apart. Direct flights take around 2h 00m, and recent direct fares were with JetSmart and Sky Airline. Over the next few months, one-way fares start from $30, and November 2026 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Santiago to Antofagasta?

The cheapest one-way fare we've seen recently is $30 with JetSmart, departing Thursday, November 12, 2026. Over the coming months, the lowest fare in each month ranges from $30 to $34.

What is the cheapest month to fly from Santiago to Antofagasta?

November 2026 currently has the lowest fares, from $30 one way.

Are there direct flights from Santiago to Antofagasta?

Yes. Recent direct fares were with JetSmart and Sky Airline.

How long is the flight from Santiago to Antofagasta?

A direct flight takes about 2h 00m. Santiago and Antofagasta are around 1,090 km apart.

Which airlines fly from Santiago to Antofagasta?

Recent fares on this route were with JetSmart and Sky Airline.

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