Cheap flights from Antofagasta to Santiago

One-way fares from $30 · ANF → SCL · prices found by travellers in the last 48 hours

Compare all dates Santiago → Antofagasta
Cheapest fare
$30

Sky Airline · Mon, Nov 30

Cheapest month
November

from $30

Direct flights
Yes

Sky Airline and LATAM Airlines Group

Flight time
1h 51m

1,090 km

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Cheapest month to fly from Antofagasta to Santiago

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 Cheapest $30
  2. February 2027 $44

Cheapest dates in November 2026

The lowest fares we've seen for each day, cheapest first.

Sky Airline
Depart21:25 Mon, Nov 30ANF → SCL 1h 54m · Direct
$30one way, per person
View deal
Sky Airline
Depart16:58 Sun, Nov 29ANF → SCL 1h 54m · Direct
$31one way, per person
View deal
Sky Airline
Depart20:00 Tue, Nov 24ANF → SCL 1h 54m · Direct
$35one way, per person
View deal
LATAM Airlines Group
Depart23:40 Wed, Nov 25ANF → SCL 1h 51m · Direct
$39one way, per person
View deal
Sky Airline
Depart21:35 Wed, Nov 18ANF → SCL 1h 54m · Direct
$49one way, per person
View deal
Sky Airline
Depart08:48 Wed, Nov 11ANF → SCL 1h 54m · Direct
$54one way, per person
View deal
JetSmart
Depart16:23 Thu, Nov 12ANF → SCL 2h 28m · 1 stop
$81one way, per person
View deal
LATAM Airlines Group
Depart13:54 Thu, Nov 5ANF → SCL 2h 20m · 1 stop
$112one way, per person
View deal
See every date in November 2026 →

Plan the rest of your trip to Santiago

Where to stay, what to do and getting around, from our travel partners.

Where to stay

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Things to do

Things to do in SantiagoTours, attractions and day trips on Klook Explore →

Getting around

Airport transfer in SantiagoPre-book a driver to meet you at arrivals, with Kiwitaxi Book a transfer → Car hire in SantiagoCompare rental cars from major brands on EconomyBookings Compare cars →

About flights from Antofagasta to Santiago

Antofagasta (ANF) and Santiago (SCL) are about 1,090 km apart. Direct flights take around 1h 51m, and recent direct fares were with Sky Airline and LATAM Airlines Group. Over the next few months, one-way fares start from $30, and November 2026 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Antofagasta to Santiago?

The cheapest one-way fare we've seen recently is $30 with Sky Airline, departing Monday, November 30, 2026. Over the coming months, the lowest fare in each month ranges from $30 to $44.

What is the cheapest month to fly from Antofagasta to Santiago?

November 2026 currently has the lowest fares, from $30 one way.

Are there direct flights from Antofagasta to Santiago?

Yes. Recent direct fares were with Sky Airline and LATAM Airlines Group.

How long is the flight from Antofagasta to Santiago?

A direct flight takes about 1h 51m. Antofagasta and Santiago are around 1,090 km apart.

Which airlines fly from Antofagasta to Santiago?

Recent fares on this route were with Sky Airline, LATAM Airlines Group and JetSmart.

More cheap flights from Antofagasta

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