- Cheapest fare
- $468
- Cheapest month
- December
- Direct flights
- Not recently
- Quickest trip
- 9h 20m
Copa Airlines · Mon, Dec 28
from $468
Usually 1+ stop
5,780 km
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Cheapest month to fly from Santiago to Santo Domingo
Lowest one-way fare per person in each month. Choose a month to see every date.
Cheapest dates in December 2026
The lowest fares we've seen for each day, cheapest first.
Plan the rest of your trip to Santo Domingo
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About flights from Santiago to Santo Domingo
Santiago (SCL) and Santo Domingo (SDQ) are about 5,780 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 9h 20m. Over the next few months, one-way fares start from $468, and December 2026 is currently the cheapest month to fly.
These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.
Frequently asked questions
How much is a flight from Santiago to Santo Domingo?
The cheapest one-way fare we've seen recently is $468 with Copa Airlines, departing Monday, December 28, 2026.
What is the cheapest month to fly from Santiago to Santo Domingo?
December 2026 currently has the lowest fares, from $468 one way.
Are there direct flights from Santiago to Santo Domingo?
We haven't seen direct fares recently, so most journeys include at least one stop.
How long is the flight from Santiago to Santo Domingo?
The quickest journey we've seen takes about 9h 20m. Santiago and Santo Domingo are around 5,780 km apart.
Which airlines fly from Santiago to Santo Domingo?
Recent fares on this route were with Copa Airlines.
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