Cheap flights from Santiago to Sao Paulo

One-way fares from $125 · SCL → SAO · prices found by travellers in the last 48 hours

Cheapest fare
$125

Sky Airline · Fri, Feb 26

Cheapest month
February

from $125

Direct flights
Yes

Sky Airline

Flight time
3h 50m

2,590 km

Get a price alert

We'll email you when Santiago → Sao Paulo drops to your price. It's free, and you can stop any time.

Today's cheapest fare is $125. We'll send one email to confirm. See our privacy policy.

Cheapest month to fly from Santiago to Sao Paulo

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 $162
  2. December 2026 $127
  3. January 2027 $152
  4. February 2027 Cheapest $125
  5. March 2027 $127
  6. April 2027 $165
  7. May 2027 $169
  8. September 2027 $193
  9. October 2027 $327

Cheapest dates in February 2027

The lowest fares we've seen for each day, cheapest first.

Sky Airline
Depart07:45 Fri, Feb 26SCL → GRU 3h 55m · Direct
$125one way, per person
View deal
Sky Airline
Depart07:45 Sat, Feb 27SCL → GRU 3h 55m · Direct
$125one way, per person
View deal
Sky Airline
Depart07:45 Thu, Feb 25SCL → GRU 3h 55m · Direct
$126one way, per person
View deal
Sky Airline
Depart07:45 Sat, Feb 20SCL → GRU 3h 55m · Direct
$162one way, per person
View deal
Sky Airline
Depart07:45 Fri, Feb 19SCL → GRU 3h 55m · Direct
$169one way, per person
View deal
See every date in February 2027 →

Plan the rest of your trip to Sao Paulo

Where to stay, what to do and getting around, from our travel partners.

About flights from Santiago to Sao Paulo

Santiago (SCL) and Sao Paulo (SAO) are about 2,590 km apart. Direct flights take around 3h 50m, and recent direct fares were with Sky Airline. Over the next few months, one-way fares start from $125, and February 2027 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Santiago to Sao Paulo?

The cheapest one-way fare we've seen recently is $125 with Sky Airline, departing Friday, February 26, 2027. Over the coming months, the lowest fare in each month ranges from $125 to $327.

What is the cheapest month to fly from Santiago to Sao Paulo?

February 2027 currently has the lowest fares, from $125 one way.

Are there direct flights from Santiago to Sao Paulo?

Yes. Recent direct fares were with Sky Airline.

How long is the flight from Santiago to Sao Paulo?

A direct flight takes about 3h 50m. Santiago and Sao Paulo are around 2,590 km apart.

Which airlines fly from Santiago to Sao Paulo?

Recent fares on this route were with Sky Airline and avianca airlines.

More cheap flights from Santiago

Compare flights to Sao Paulo from other cities →