Cheap flights from Sao Paulo to Santiago

One-way fares from $111 · SAO → SCL · prices found by travellers in the last 48 hours

Cheapest fare
$111

Sky Airline · Tue, Mar 9

Cheapest month
March

from $111

Direct flights
Yes

Sky Airline and JetSmart

Flight time
4h 10m

2,590 km

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Cheapest month to fly from Sao Paulo to Santiago

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 $114
  2. December 2026 $121
  3. January 2027 $114
  4. February 2027 $114
  5. March 2027 Cheapest $111
  6. April 2027 $158
  7. May 2027 $112
  8. June 2027 $144
  9. August 2027 $177
  10. September 2027 $194
  11. October 2027 $406

Cheapest dates in March 2027

The lowest fares we've seen for each day, cheapest first.

Sky Airline
Depart13:00 Tue, Mar 9GRU → SCL 4h 10m · Direct
$111one way, per person
View deal
Sky Airline
Depart12:55 Sat, Mar 13GRU → SCL 4h 10m · Direct
$114one way, per person
View deal
Sky Airline
Depart13:00 Fri, Mar 26GRU → SCL 4h 10m · Direct
$155one way, per person
View deal
Sky Airline
Depart13:00 Wed, Mar 17GRU → SCL 4h 10m · Direct
$159one way, per person
View deal
See every date in March 2027 →

Plan the rest of your trip to Santiago

Where to stay, what to do and getting around, from our travel partners.

About flights from Sao Paulo to Santiago

Sao Paulo (SAO) and Santiago (SCL) are about 2,590 km apart. Direct flights take around 4h 10m, and recent direct fares were with Sky Airline and JetSmart. Over the next few months, one-way fares start from $111, and March 2027 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Sao Paulo to Santiago?

The cheapest one-way fare we've seen recently is $111 with Sky Airline, departing Tuesday, March 9, 2027. Over the coming months, the lowest fare in each month ranges from $111 to $406.

What is the cheapest month to fly from Sao Paulo to Santiago?

March 2027 currently has the lowest fares, from $111 one way.

Are there direct flights from Sao Paulo to Santiago?

Yes. Recent direct fares were with Sky Airline and JetSmart.

How long is the flight from Sao Paulo to Santiago?

A direct flight takes about 4h 10m. Sao Paulo and Santiago are around 2,590 km apart.

Which airlines fly from Sao Paulo to Santiago?

Recent fares on this route were with Sky Airline, JetSmart and avianca airlines.

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