Cheap flights from Sao Paulo to Panama City

One-way fares from $279 · SAO → PTY · prices found by travellers in the last 48 hours

Compare all dates Panama City → Sao Paulo
Cheapest fare
$279

avianca airlines · Wed, Dec 2

Cheapest month
December

from $279

Direct flights
Not recently

Usually 1+ stop

Quickest trip
7h 45m

5,090 km

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Cheapest month to fly from Sao Paulo to Panama City

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 $295
  2. December 2026 Cheapest $279
  3. January 2027 $307
  4. March 2027 $306

Cheapest dates in December 2026

The lowest fares we've seen for each day, cheapest first.

avianca airlines
Depart07:55 Wed, Dec 2GRU → PTY 7h 50m · 1 stop
$279one way, per person
View deal
avianca airlines
Depart07:55 Fri, Dec 4GRU → PTY 7h 45m · 1 stop
$296one way, per person
View deal
avianca airlines
Depart17:25 Thu, Dec 3GRU → PTY 8h 00m · 1 stop
$297one way, per person
View deal
avianca airlines
Depart07:55 Sat, Dec 12GRU → PTY 7h 50m · 1 stop
$407one way, per person
View deal
avianca airlines
Depart07:55 Fri, Dec 18GRU → PTY 7h 50m · 1 stop
$426one way, per person
View deal
avianca airlines
Depart07:55 Sat, Dec 19GRU → PTY 7h 45m · 1 stop
$436one way, per person
View deal
avianca airlines
Depart00:25 Wed, Dec 23GRU → PTY 7h 50m · 1 stop
$530one way, per person
View deal
LATAM Airlines Brasil
Depart23:40 Wed, Dec 30GRU → PTY 11h 30m · 3 stops
$630one way, per person
View deal
See every date in December 2026 →

Plan the rest of your trip to Panama City

Where to stay, what to do and getting around, from our travel partners.

Where to stay

Hotels in Panama CityCompare places to stay on Booking.com Find hotels →

Things to do

Things to do in Panama CityTours, attractions and day trips on Klook Explore →

Getting around

Airport transfer in Panama CityPre-book a driver to meet you at arrivals, with Kiwitaxi Book a transfer → Car hire in Panama CityCompare rental cars from major brands on EconomyBookings Compare cars →

About flights from Sao Paulo to Panama City

Sao Paulo (SAO) and Panama City (PTY) are about 5,090 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 7h 45m. Over the next few months, one-way fares start from $279, and December 2026 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Sao Paulo to Panama City?

The cheapest one-way fare we've seen recently is $279 with avianca airlines, departing Wednesday, December 2, 2026. Over the coming months, the lowest fare in each month ranges from $279 to $307.

What is the cheapest month to fly from Sao Paulo to Panama City?

December 2026 currently has the lowest fares, from $279 one way.

Are there direct flights from Sao Paulo to Panama City?

We haven't seen direct fares recently, so most journeys include at least one stop.

How long is the flight from Sao Paulo to Panama City?

The quickest journey we've seen takes about 7h 45m. Sao Paulo and Panama City are around 5,090 km apart.

Which airlines fly from Sao Paulo to Panama City?

Recent fares on this route were with avianca airlines and LATAM Airlines Brasil.

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